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Male reproductive system — A/L Biology

Aligned with the NIE syllabus

What must I remember about Male reproductive system?

  • The male reproductive system consists of primary sex organs (paired testes) and accessory structures: epididymides, vas deferens, ejaculatory ducts, urethra, penis, and accessory glands (seminal vesicles, prostate, bulbourethral glands).
  • Testes are housed outside the abdominal cavity in the scrotum to maintain a scrotal temperature ~2-3°C below core body temperature, required for viable spermatogenesis.
  • Seminiferous tubules contain Sertoli cells (nourish developing sperm, form the blood-testis barrier, and secrete androgen-binding protein and inhibin) and spermatogenic germ cells undergoing spermatogenesis.
  • Leydig cells (interstitial cells) located between seminiferous tubules synthesize and secrete testosterone in response to Luteinizing Hormone (LH / ICSH) from anterior pituitary.
  • Accessory glands produce semen: Seminal vesicles contribute ~60% volume (alkaline, fructose for sperm ATP, prostaglandins, coagulating enzyme); Prostate contributes ~30% (milky, slightly acidic, citrate, PSA enzyme); Bulbourethral glands secrete alkaline mucus neutralizing residual urine.

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  1. Hormonal axis in males

    GnRH from hypothalamus stimulates anterior pituitary to secrete FSH (stimulates Sertoli cells for spermatogenesis) and LH (stimulates Leydig cells to produce Testosterone); Testosterone and Inhibin exert negative feedback on hypothalamus and pituitary.

  2. Sperm ultrastructure

    Head contains haploid nucleus and Acrosome (hydrolytic enzymes like hyaluronidase for egg penetration); Midpiece packed with mitochondria for ATP generation; Tail (flagellum with 9+2 axoneme) for motility.

  3. Spermatogenesis vs Spermiogenesis

    Spermatogenesis is the complete developmental sequence from spermatogonium to mature sperm; Spermiogenesis is the specific maturation phase converting non-motile spermatids into flagellated spermatozoa.

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Source: NIE G.C.E. (A/L) Biology Syllabus & Resource Book, Unit 5

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Year 2 · Term 1

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