Nervous system disorders — A/L Biology

How do I practise Nervous system disorders?

1 question with a worked solution

1. Parkinson's disease is neurobiologically characterized by the progressive degeneration of dopamine-producing neurons primarily in which brain region?
   1. A) Vermis of the cerebellum
   2. B) Prefrontal cerebral cortex
   3. C) Substantia nigra of the midbrain (basal nuclei)
   4. D) Hippocampus of the limbic system
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   Correct answer: C) Substantia nigra of the midbrain (basal nuclei)

   Parkinson's disease results from the death of dopaminergic neurons in the substantia nigra, leading to dopamine deficiency in the basal nuclei and symptoms like resting tremors, rigidity, and bradykinesia.

   Show worked solution

   Step 1: Review neurodegenerative diseases: - Alzheimer's: beta-amyloid plaques in hippocampus and cerebral cortex. - Parkinson's: loss of dopaminergic neurons in substantia nigra. Step 2: Substantia nigra dopamine depletion causes characteristic motor dysfunction. Answer: Substantia nigra of the midbrain (basal nuclei).
   Modelled on: the A/L Biology examination pattern

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Where does Nervous system disorders fit in the syllabus?

Year 2 · Term 1